Search on: FACTOR-PROLINE DIOXYGENASES, HYPOXIA-INDUCIBLE 
Descriptors Found: 1
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Descriptor English:   Hypoxia-Inducible Factor-Proline Dioxygenases 
Descriptor Spanish:   Prolina Dioxigenasas del Factor Inducible por Hipoxia 
Descriptor Portuguese:   Prolina Dioxigenases do Fator Induzível por Hipóxia 
Synonyms English:   Dioxygenase, Hypoxia-Inducible Factor-Proline
Dioxygenases, Hypoxia-Inducible Factor-Proline
Egl Nine Homolog 1 Protein
Egl Nine Homolog 2 Protein
Egl Nine Homolog 3 Protein
Factor-Proline Dioxygenase, Hypoxia-Inducible
Factor-Proline Dioxygenases, Hypoxia-Inducible
HIF Prolyl 4 Hydroxylase
HIF Prolyl 4 Hydroxylases
HIF Prolyl-4-Hydroxylase
HIF Prolyl-4-Hydroxylases
Hypoxia Inducible Factor Proline Dioxygenase
Hypoxia Inducible Factor Proline Dioxygenases
Hypoxia Inducible Factor Prolyl Hydroxylase 1
Hypoxia Inducible Factor Prolyl Hydroxylase 2
Hypoxia Inducible Factor Prolyl Hydroxylase 3
Hypoxia-Inducible Factor Prolyl Hydroxylase 1
Hypoxia-Inducible Factor Prolyl Hydroxylase 2
Hypoxia-Inducible Factor Prolyl Hydroxylase 3
Hypoxia-Inducible Factor-Proline Dioxygenase
Prolyl-4-Hydroxylase, HIF
Prolyl-4-Hydroxylases, HIF  
Tree Number:   D08.811.682.690.416.617.500
D08.811.682.690.708.694.500
Definition English:   Dioxygenase enzymes that specifically hydroxylate a PROLINE residue on the HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. They are OXYGEN-dependent enzymes that play an important role in mediating cellular adaptive responses to HYPOXIA. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   55296 
Unique Identifier:   D064799 

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